PP-066 Effect of adeforvir dipivoxil on HBcAg-specific cytotoxic T cells in patients with chronic hepatitis B
نویسندگان
چکیده
منابع مشابه
interleukin-7 in patients with chronic hepatitis b may have effect on t follicular helper cells and specific cellular immunity
conclusions this study suggests that the il-7 level of chb patients may be related to tfh cells. in chb patients, il-7 possibly increases the level of tfh cells and hbv-specific cellular immune responses and thereby reduces the hbv dna level. background in patients with chronic hepatitis b (chb), the relation of interkeukin-7 (il-7) to either the t follicular helper cells (tfh cells) or to a sp...
متن کاملAdefovir dipivoxil modulates cytokine expression in Th1/Th2 cells in patients with chronic hepatitis B.
The impact of adefovir dipivoxil (ADV) treatment on the immune system in patients with chronic hepatitis B (CHB) is unknown. The present study was designed to determine the expression of six cytokines, IL-2, IFN-γ, TNF-α, IL-4, IL-6 and IL-10, and their correlation with liver functions and clinical responses to ADV treatment. A total of 22 CHB patients were treated with ADV at a daily oral dose...
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We developed an immunogen to stimulate multivalent immunity against hepatitis B surface antigen (HBsAg) and hepatitis B core antigens (HBcAg). Immune responses specific for both HBsAg and HBcAg play an important role in controlling the infection. HBsAg-specific antibodies mediate elimination of virions at an early stage of infection and prevent the spread of virus. The immunogen was constructed...
متن کاملExpression of HBsAg and HBcAg in the ovaries and ova of patients with chronic hepatitis B.
AIM To investigate the expression and distribution of HBV in the ovaries and ova. METHODS The immunohistochemistry method was used to detect the HBsAg and HBcAg in the ovaries of patients with chronic hepatitis B. RESULTS Expression of HBsAg in the ova, granular and interstitial cells of the ovaries was located in the cytomembrane and cytoplasm. Expression of HBcAg in the ova, granular, int...
متن کاملInterleukin-7 in Patients With Chronic Hepatitis B May Have Effect on T Follicular Helper Cells and Specific Cellular Immunity
BACKGROUND In patients with chronic hepatitis B (CHB), the relation of interkeukin-7 (IL-7) to either the T follicular helper cells (Tfh cells) or to a specific cellular immune response is not clear. OBJECTIVES The present study aims to explore the possible relationship of IL-7 to Tfh cells and to hepatitis B virus (HBV)-specific cellular immune response in patients with CHB. METHODS Ninety...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2009
ISSN: 1201-9712
DOI: 10.1016/s1201-9712(09)60460-4